Answers, Links and Info

Our Most Frequently Asked Questions


The choice of the dispenser depends on the requirements of the experiment setup.

-- For special liquid handling in a pL-volume range, the PDMD is a good choice.

-- If you want to dispense between several nL and a few µL, the M2MD AD would be most appropriate.

-- If you want to dispense the same liquid several times, you can use the M2MD BD. For further information, please contact us.


  • What is the typical customer journey from first contact to finished product?

Our intention in the early stages, after first contact, is to establish a deep understanding of your individual application needs. We offer a free demo or feasibility study as part of this process, and we can also arrange for production on a pilot-scale level with our Contract Manufacturing Service (CMS) if needed, along with assay development. Our aim is to achieve a perfect understanding of your needs, so that we can create and configure the absolute best and most perfectly tailored solution for your application.

Once your specific needs are clearly established and you are happy to proceed, the building of your solution can begin, and it will be managed and executed by our expert team in Berlin. Once the build is complete, you may visit us to collect your microdispensing instrument and receive training on how to use it properly. Alternatively, we can deliver it to you and train you on site at your location.

After you've got your instrument and had your training, we continue to support you as needed with our after-care service, provided by our team of M2 experts.


  • What is the advantage of a vacuum table compared to a planar target holder?

The advantage of the vacuum table is that you can affix to it every kind of target you want to spot on.


  • My targets have a very unique shape. Is it possible to request a custom-tailored solution/target table?

Yes, this is possible. Based on your requirements, our CAD department will create a model specifically for you.


  • What is the difference between a Single-Channel Syringe and a Dual-Channel Syringe?
    With the Single-Channel Syringe Pump, you can use one system liquid. With the Dual-Channel Syringe Pump, you can use two system liquids.

(We recommend using ultra-pure water as the first system liquid. Liquid alcohol, for example, can be used as the second system liquid. Alcohol can be used for the degassing of the system as well as disinfection.)


  • Are the dispenser heads interchangeable?



  • How long is the set-up time in the event of a dispenser change?

The change between a PDMD and an M2MD only requires 1-2 minutes.


  • How can I find out if the iZERO, iONE or iTWO is most suitable for my application?

Initially, an assessment of your specific project needs would be carried out in order to identify which of the three systems would be best suited to your requirements.  Additionally, we offer a general trial run at our premises.

In terms of a full process optimization, we work closely and directly with our clients in order to make sure that they receive the best solution for their purposes.  Furthermore, our services include training and after-care.


  • Is it possible to have multiple users on a single machine?

Absolutely. Our own InDOT software is capable of handling multiple users with individual runs and applications.


  • What kind of system liquids can be applied?

The fluid path for the iZERO, iONE and iTWO systems is capable of handling commonly used solvents as well as more aggressive substances, such as DMSO. Nevertheless, we recommend using ultra-pure water as the first system liquid. Liquid alcohol, for example, can be used as the second system liquid.


  • I have a special laboratory setup. How can I find out if the iZERO iONE or iTWO is suitable for my experiment setup?

Please contact us if you have any questions. We will check your requirements and give you an overview of the options, which will be aligned with the requirements of your particular laboratory setup.


  • Can I use all kinds of solutions?

The limitation is defined by a solution's dynamic viscosity. A viscosity of up to 8.4 mPas is possible to dispense.


  • Is it possible to use different spotting parameters for the samples to be dispensed?

Yes, it is possible. The parameters can be defined in the pattern.



  • Can M2-Automation microdispensing systems be connected to the internet?

Under no circumstances should the systems be connected to the internet.  The built-in PC must never be used for applications not authorised by M2-Automation. There is a serious risk of reducing system speed and introducing bugs.


  • Where do I find the Ordinance on Hazardous Substances?

The Ordinance on Hazardous Substances is available on the website of the German Federal Institute for Occupational Safety and Health.


Get in touch

If you have further questions, please don't hesitate to contact us.